Sodium bis(2-methoxyethoxy)aluminum hydride

• Catalog No.: A13292
• CAS Number: 22722-98-1
• M. F.: C6H15AlNaO4
• M. W.: 201.152208
• Purity: 70% w/w in toluene.

SYNONYMS

• Title: 双(2-甲氧基乙氧基)氢化铝钠
• IUPAC name: sodium 2,5,7,10-tetraoxa-6-aluminaundecan-6-uide
• IUPAC Traditional name: sodium 2,5,7,10-tetraoxa-6-aluminaundecan-6-uide
• Synonyms: Sodium dihydrobis(2-methoxyethoxy)aluminate

DATABASE IDS

• MDL Number: MFCD00011631
• CAS Number: 22722-98-1
• EC Number: 245-178-2
• Merck Index: 148565

PROPERTIES

• Purity: 70% w/w in toluene.
• Density: 1.020
• Flash Point: 4°C(39°F)
• GHS Hazard statements: H224-H260-H314-H318-H361-H373-H336
• European Hazard Symbols: X
• European Hazard Symbols: Corrosive (C)
• European Hazard Symbols: Flammable (F)
• GHS Precautionary statements: P210-P231+P232-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 11-14/15-34-48/20-63
• Safety Statements: 7/8-9-16-20-23-26-30-33-36/37/39-43h-...
• Storage Warning: Moisture Sensitive
• TSCA Listed: 是
• Hazard Class: 4.3
• UN Number: UN3399
• Packing Group: I

REFERENCES

• For use as a superior activator/initiator for the formation of Grignard reagents, see: Coll. Czech. Chem. Commun., 38, 1614 (1973).
• Convenient alternative to lithium aluminum hydride for many reductions: Coll. Czech. Chem. Commun., 34, 118 (1969). The reagent is more readily and safely handled, is more stable to air and can be used at high temperatures. For use in the stereospecific reduction of 2-yn-1-ols to (E)-allylic alcohols, and reviews, see: Org. Synth. Coll., 7, 524 (1990):
  
• The reducing properties can be modified by addition of one mole of ethanol, which gives a reagent for the reduction of lactones to lactols, or one mole of N-methylpiperazine or morpholine, which gives a reagent for the high-yield reduction of esters to aldehydes: Synthesis, 526 (1976).