(Cyanomethyl)triphenylphosphonium chloride

• Catalog No.: A13096
• CAS Number: 4336-70-3
• M. F.: C20H17ClNP
• M. W.: 337.782441
• Purity: 98+%

SYNONYMS

• Title: (氰甲基)三苯基氯化磷鎓
• IUPAC name: (cyanomethyl)triphenylphosphanium chloride
• IUPAC Traditional name: (cyanomethyl)triphenylphosphanium chloride

DATABASE IDS

• CAS Number: 4336-70-3
• MDL Number: MFCD00031672
• EC Number: 224-383-0
• Beilstein Number: 6222047

PROPERTIES

• Purity: 98+%
• Melting Point: ca 270°C dec.
• GHS Hazard statements: H331-H302-H312-H315-H319-H335
• European Hazard Symbols: X
• GHS Precautionary statements: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• Risk Statements: 20/21/22-36/37/38
• RTECS: TA2075000
• Safety Statements: 26-36/37
• Storage Warning: Hygroscopic
• TSCA Listed: 否
• Hazard Class: 6.1
• UN Number: UN3439
• Packing Group: III

REFERENCES

• Forms a moderately stable crystalline ylide which reacts with aldehydes to give ɑ?-unsaturated nitriles, predominantly as their (Z)-isomers: Chem. Ber., 94, 578 (1961); J. Chem. Soc., 1266 (1961); Appendix 1.
• Further deprotonation of the phosphorane with sodium bis(trimethylsilyl)amide followed by C-alkylation generates a homologated phosphorane: Angew. Chem. Int. Ed., 26, 79 (1987).
• Reaction of the ylide with carboxylic acids in the presence of EDCI (1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, A10807) and DMAP, followed by ozonolysis of the resulting acylphosphoranes, provides a novel route to the homologous ɑ-keto esters: J. Org. Chem., 59, 4364 (1994):