Diethyl 2,2-diethoxyethylphosphonate

• Catalog No.: A12461
• CAS Number: 7598-61-0
• M. F.: C10H23O5P
• M. W.: 254.260381
• Purity: 96%

SYNONYMS

• Title: 2,2-二乙氧基乙基磷酸二乙酯
• IUPAC name: diethyl (2,2-diethoxyethyl)phosphonate
• IUPAC Traditional name: diethyl 2,2-diethoxyethylphosphonate
• Synonyms: Diethyl phosphonoacetaldehyde diethyl acetal; 2,2-Diethoxyethylphosphonic acid diethyl ester

DATABASE IDS

• CAS Number: 7598-61-0
• MDL Number: MFCD00009236
• EC Number: 231-504-0
• Beilstein Number: 1785614

PROPERTIES

• Purity: 96%
• Boiling Point: 101-103°C/8mm
• Density: 1.052
• Flash Point: >110°C(230°F)
• Refractive Index: 1.4278
• GHS Hazard statements: H315-H319
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P280-P305+P351+P338-P302+P352-P321-P362-P332+P313
• Risk Statements: 36/38
• Safety Statements: 26-37
• Storage Warning: Moisture Sensitive
• TSCA Listed: 否

REFERENCES

• Wadsworth-Emmons olefination with aldehydes leads to ɑ?-enals: Bull. Chem. Soc. Jpn., 30, 1498 (1962). This reaction fails for ketones since the ylide loses EtO^-. This can be avoided by prior conversion of the acetal to the corresponding cyclohexyl enamine: Org. Synth. Coll., 6, 448 (1988), followed by reaction with the ketone: Org. Synth. Coll., 6, 358 (1988):