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6-Chloronicotinoyl chloride_Molecular_structure_CAS_58757-38-3)
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6-Chloronicotinoyl chloride

Catalog No. A12354 Name Alfa Aesar
CAS Number 58757-38-3 Website
M. F. C6H3Cl2NO Telephone
M. W. 176.00012 Fax
Purity 98% Email
Storage Chembase ID: 84520

SYNONYMS

Title
6-氯烟酰氯
IUPAC name
6-chloropyridine-3-carbonyl chloride
IUPAC Traditional name
6-chloropyridine-3-carbonyl chloride
Synonyms
6-Chloropyridine-3-carbonyl chloride

DATABASE IDS

MDL Number MFCD00051775
CAS Number 58757-38-3
Beilstein Number 115927

PROPERTIES

Purity 98%
Boiling Point 84-85°C/3mm
Melting Point 48-52°C
GHS Pictograms GHS05
GHS Hazard statements H314-H318
European Hazard Symbols Corrosive Corrosive (C)
GHS Precautionary statements P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501A
Risk Statements 34
Safety Statements 26-36/37/39-45
Storage Warning Moisture Sensitive
TSCA Listed
Hazard Class 8
UN Number UN3261
Packing Group II

DETAILS

REFERENCES

  • Acylation of dimethyl malonate has been carried out using the combination of triethylamine and magnesium chloride (see Diethyl malonate, A15468, and Triethylamine, A12646, for discussion), followed by one-pot hydrolysis-decarboxylation of the acylmalonate derivative in wet DMSO, to give 5-acetyl-2-chloropyridine in good yield: Tetrahedron, 48, 9233 (1992).