1-Methyl-2-pyrrolidinone

• Catalog No.: A12260
• CAS Number: 872-50-4
• M. F.: C5H9NO
• M. W.: 99.13106
• Purity: 99+%

SYNONYMS

• Title: 1-甲基-2-吡咯烷酮
• IUPAC name: 1-methylpyrrolidin-2-one
• IUPAC Traditional name: methylpyrrolidone
• Synonyms: N-Methyl-2-Pyrrolidone; N-Methylbutyrolactam

DATABASE IDS

• Beilstein Number: 106420
• EC Number: 212-828-1
• CAS Number: 872-50-4
• Merck Index: 146117
• MDL Number: MFCD00003193

PROPERTIES

• Purity: 99+%
• Boiling Point: 204°C
• Density: 1.033
• Flash Point: 86°C(187°F)
• Melting Point: -24°C
• Refractive Index: 1.4705
• GHS Hazard statements: H360-H315-H319-H335-H227
• European Hazard Symbols: Toxic (T)
• GHS Precautionary statements: P210-P305+P351+P338-P302+P352-P321-P405-P501A
• Risk Statements: 61-36/37/38
• RTECS: UY5790000
• Safety Statements: 53-45
• TSCA Listed: 是

REFERENCES

• Water-miscible, high-boiling dipolar aprotic solvent, compare N,N-Dimethylformamide, A13547 and Dimethyl sulfoxide, A13280, used in a wide variety of reactions, e.g.:
• Nucleophilic displacement reactions with CN^-: J. Chem. Soc., 954 (1962). Preparation of thiophenols from unactivated aryl chlorides and Na alkanethiolates: J. Org. Chem., 56, 3728 (1991). Reaction of thiophenol and potassium carbonate in uncatalyzed substitution reactions of chloroanilines and chloroanilides: J. Org. Chem., 56, 862 (1991). Synthesis of alkylaryl and alkylheteroaryl ethers, catalyzed by Cu(I): Tetrahedron, 48, 3633 (1992).