4-Methylmorpholine

• Catalog No.: A12158
• CAS Number: 109-02-4
• M. F.: C5H11NO
• M. W.: 101.14694
• Purity: 99%

SYNONYMS

• Title: 4-甲基吗啉
• IUPAC name: 4-methylmorpholine
• IUPAC Traditional name: N-methylmorpholine
• Synonyms: NMM; N-Methylmorpholine

DATABASE IDS

• CAS Number: 109-02-4
• EC Number: 203-640-0
• MDL Number: MFCD00006175
• Merck Index: 146277
• Beilstein Number: 102719

PROPERTIES

• Purity: 99%
• Boiling Point: 116-118°C
• Density: 0.920
• Flash Point: 14°C(57°F)
• Melting Point: -65°C
• Refractive Index: 1.4355
• GHS Hazard statements: H225-H314-H318-H302-H312-H332
• European Hazard Symbols: X
• European Hazard Symbols: Corrosive (C)
• European Hazard Symbols: Flammable (F)
• GHS Precautionary statements: P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 11-20/21/22-34
• RTECS: QE5775000
• Safety Statements: 9-16-26-36/37/39-45-60
• TSCA Listed: 是
• Hazard Class: 3
• UN Number: UN2535
• Packing Group: II

REFERENCES

• Widely used base in peptide chemistry, milder than triethylamine. Recommended for the avoidance of racemization in the mixed anhydride method of coupling: J. Am. Chem. Soc., 88, 1338 (1966); 89, 5012 (1967). Also preferred in many cases for the formation of active esters or the neutralization of acid salts. For peptide reagents, see Appendix 6.