N-(Benzyloxycarbonyloxy)succinimide

• Catalog No.: A12153
• CAS Number: 13139-17-8
• M. F.: C12H11NO5
• M. W.: 249.21944
• Purity: 99%

SYNONYMS

• Title: N-(苄氧基羰基氧基)丁二酰亚胺
• IUPAC name: benzyl 2,5-dioxopyrrolidin-1-yl carbonate
• IUPAC Traditional name: benzyl 2,5-dioxopyrrolidin-1-yl carbonate
• Synonyms: Cbz-ONSu; Benzyl N-succinimidyl carbonate

DATABASE IDS

• EC Number: 236-075-3
• MDL Number: MFCD00005513
• CAS Number: 13139-17-8
• Beilstein Number: 1387927

PROPERTIES

• Purity: 99%
• Melting Point: 77-82°C
• Storage Warning: Moisture Sensitive
• TSCA Listed: 否

REFERENCES

• Selective reagent for the introduction of the benzyloxycarbonyl (Cbz or Z) protecting group, avoiding the formation of amino acid dimers: Tetrahedron Lett., 4765 (1966); J. Antibiot., 25, 695 (1972); 34, 513 (1981); Can. J. Chem., 60, 976 (1982).
• Especially convenient for the selective protection of the -amino group of lysine and ornithine: Can. J. Chem., 54, 733 (1976); Rec. Trav. Chim.,99, 400 (1980). See Appendix 6.