Chloromethyl pivalate

• Catalog No.: A11967
• CAS Number: 18997-19-8
• M. F.: C6H11ClO2
• M. W.: 150.60334
• Purity: 97%

SYNONYMS

• Title: 新戊酸氯甲酯
• IUPAC name: chloromethyl 2,2-dimethylpropanoate
• IUPAC Traditional name: chloromethyl 2,2-dimethylpropanoate
• Synonyms: Chloromethyl trimethylacetate; Pivaloyloxymethyl chloride

DATABASE IDS

• CAS Number: 18997-19-8
• Beilstein Number: 1560838
• MDL Number: MFCD00000884
• EC Number: 242-735-1

PROPERTIES

• GHS Hazard statements: H314-H318-H226
• European Hazard Symbols: Corrosive (C)
• GHS Precautionary statements: P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 10-34
• Safety Statements: 26-36/37/39-45
• TSCA Listed: 是
• Hazard Class: 3
• UN Number: UN2924
• Packing Group: III
• Purity: 97%
• Boiling Point: 146-148°C
• Density: 1.045
• Flash Point: 40°C(104°F)
• Refractive Index: 1.4170

REFERENCES

• Reagent for the N-protection of amines, e.g. adenine in the presence of K₂CO₃ in DMF, as pivaloyloxymethyl (Pom) derivatives, which have been found useful in the synthesis of sensitive nucleosides. The Pom group is cleaved in mild base, e.g. methanolic ammonia: J. Am. Chem. Soc., 89, 5439 (1967).