1,3-Diaminopropane

• Catalog No.: A11932
• CAS Number: 109-76-2
• M. F.: C3H10N2
• M. W.: 74.1249
• Purity: 98%

SYNONYMS

• Title: 1,3-二氨基丙烷
• IUPAC name: propane-1,3-diamine
• IUPAC Traditional name: α,ω-propanediamine
• Synonyms: 1,3-Propanediamine; Trimethylenediamine

DATABASE IDS

• CAS Number: 109-76-2
• MDL Number: MFCD00008228
• EC Number: 203-702-7
• Beilstein Number: 605277

PROPERTIES

• Purity: 98%
• Boiling Point: 134-136°C
• Density: 0.888
• Flash Point: 48°C(118°F)
• Melting Point: -12°C
• Refractive Index: 1.4573
• GHS Hazard statements: H310-H302-H314-H318-H226
• European Hazard Symbols: Toxic (T)
• GHS Precautionary statements: P280-P305+P351+P338-P309-P310
• Risk Statements: 10-22-24-35
• RTECS: TX6825000
• Safety Statements: 26-36/37/39-45
• Storage Warning: Air Sensitive
• TSCA Listed: 是
• Hazard Class: 8
• UN Number: UN2734
• Packing Group: II

REFERENCES

• The potassium derivative (KAPA) is a very strong base, valuable for its ability to cause the migration of acetylenic unsaturation to the terminal positions of alkynes (known as the "zip" reaction). In the presence of excess amine, reaction occurs within seconds; the driving force is the formation of a stable acetylide anion: J. Am. Chem. Soc., 97, 891 (1975). For example, with acetylenic carbinols: J. Chem. Soc., Chem. Commun., 959 (1976); Tetrahedron Lett., 2565 (1976); Can. J. Chem., 62, 1333 (1984). For a further example (2- to 9-decynol), using a combination of Potassium tert-butoxide, A13947, and Li 3-aminopropanamide, see: Org. Synth. Coll., 8, 146 (1993). This technique avoids the use of KH. For the use of KAPA for the isomerization of ?-pinene to the thermodynamically-more stable ɑ-pinene, see: Org. Synth. Coll., 8, 553 (1993).
• For procedures for the generation of Na or K 3-amino-propylamides from the metals by ultrasound irradiation or in the presence of Fe(NO₃)₃, see: J. Org. Chem., 49, 2494 (1984).