tert-Butyl ethyl malonate

• Catalog No.: A11927
• CAS Number: 32864-38-3
• M. F.: C9H16O4
• M. W.: 188.22094
• Purity: 95%

SYNONYMS

• Title: 丙二酸叔丁基乙基酯
• IUPAC name: 1-tert-butyl 3-ethyl propanedioate
• IUPAC Traditional name: 1-tert-butyl 3-ethyl propanedioate
• Synonyms: Malonic acid tert-butyl ethyl ester

DATABASE IDS

• MDL Number: MFCD00009193
• EC Number: 251-269-8
• Beilstein Number: 1776681
• CAS Number: 32864-38-3

PROPERTIES

• Purity: 95%
• Boiling Point: 98-100°C/22mm
• Density: 0.994
• Flash Point: 87°C(188°F)
• Refractive Index: 1.4160
• GHS Hazard statements: H227
• GHS Precautionary statements: P210-P280-P370+P378A-P403+P235-P501A
• TSCA Listed: 否

REFERENCES

• Alternative to, e.g. Diethyl malonate, A15468, permitting selective cleavage of either ester group: t-butyl with mild acid, or ethyl with aqueous alkali. For an example in cephalosporin synthesis, see: J. Antibiot., 39, 1236 (1986). Has also been used in a peptide-type synthesis: Angew. Chem. Int. Ed., 31, 785 (1992); and the synthesis of amino acid derivatives: J. Chem. Soc., Perkin 1, 1053 (1992)