Hexamethyldisiloxane

• Catalog No.: A11848
• CAS Number: 107-46-0
• M. F.: C6H18OSi2
• M. W.: 162.37752
• Purity: 98+%

SYNONYMS

• Title: 六甲基二硅氧烷
• IUPAC name: trimethyl[(trimethylsilyl)oxy]silane
• IUPAC Traditional name: hexamethyldisiloxane
• Synonyms: HMDSO

DATABASE IDS

• MDL Number: MFCD00008265
• EC Number: 203-492-7
• CAS Number: 107-46-0
• Beilstein Number: 1736258

PROPERTIES

• Purity: 98+%
• Boiling Point: 100-101°C
• Density: 0.764
• Flash Point: -2°C(28°F)
• Melting Point: -67°C
• Refractive Index: 1.3770
• GHS Hazard statements: H225-H400-H410
• European Hazard Symbols: Flammable (F)
• European Hazard Symbols: Nature polluting (N)
• GHS Precautionary statements: P210-P273-P403
• Risk Statements: 11-50/53
• RTECS: JM9237000
• Safety Statements: 9-16-60-61
• TSCA Listed: 是
• Hazard Class: 3
• UN Number: UN1993
• Packing Group: II

REFERENCES

• Silylates primary and sec-alcohols and phenols, in the presence of p-TsOH as catalyst. If the substrate contains acid-sensitive groups, PPTS can be used: Tetrahedron Lett., 4261 (1978). See Appendix 4.
• Reacts with P₂O₅ to give trimethylsilyl polyphosphate ('PPSE'), a milder and more convenient dehydrating agent then polyphosphoric acid. For examples, and related reagents, see Phosphorus(V) oxide, A13348.
• In the presence of FeCl₃, reacts with benzotrichlorides to give substituted benzoyl chlorides in good yields: J. Chem. Soc., Chem. Commun., 808 (1977).