Nitromethane

• Catalog No.: A11806
• CAS Number: 75-52-5
• M. F.: CH3NO2
• M. W.: 61.04002
• Purity: 98+%

SYNONYMS

• Title: 硝基甲烷
• IUPAC name: nitromethane
• IUPAC Traditional name: nitromethane

DATABASE IDS

• Beilstein Number: 1698205
• Merck Index: 146611
• EC Number: 200-876-6
• MDL Number: MFCD00007400
• CAS Number: 75-52-5

PROPERTIES

• Purity: 98+%
• Boiling Point: 101°C
• Density: 1.130
• Flash Point: 35°C(95°F)
• Melting Point: -29°C
• Refractive Index: 1.3820
• GHS Hazard statements: H226-H302
• European Hazard Symbols: X
• GHS Precautionary statements: P260-P370+P380+P375
• Risk Statements: 5-10-22
• RTECS: PA9800000
• Safety Statements: 41
• TSCA Listed: 是
• Hazard Class: 3
• UN Number: UN1261
• Packing Group: II

REFERENCES

• For conditions for the Henry (nitro-aldol) condensation of nitroalkanes with carbonyl compounds, see 1-Nitropropane, A11975. In the Tiffeneau-Demjanov ring expansion of ketones, the nitro aldol is reduced to the ?-hydroxyamine before diazotization; see, e.g. (cyclohexanone to cycloheptanone): Org. Synth. Coll., 4, 221 (1963); review: Org. React., 11, 157 (1960).
• For a review of the use of nitro compounds as alkyl anion synthons, including methods for removing the nitro group from the resulting carbon skeletons, see: Synthesis, 833 (1988).
• For reaction with TosMIC adducts to give pyrroles, see p-Toluenesulfonylmethyl isocyanide, A14312.
• For a brief feature on uses of this reagent in Organic synthesis, see: Synlett, 1174 (2007).