Ethyl trifluoroacetate

• Catalog No.: A11520
• CAS Number: 383-63-1
• M. F.: C4H5F3O2
• M. W.: 142.0765096
• Purity: 99%

SYNONYMS

• Title: 三氟乙酸乙酯
• IUPAC name: ethyl 2,2,2-trifluoroacetate
• IUPAC Traditional name: trifluoroethyl acetate
• Synonyms: Trifluoroacetic acid ethyl ester

DATABASE IDS

• MDL Number: MFCD00000419
• Beilstein Number: 1761411
• CAS Number: 383-63-1
• EC Number: 206-851-6

PROPERTIES

• Purity: 99%
• Boiling Point: 60-62°C
• Density: 1.192
• Flash Point: -1°C(30°F)
• Melting Point: <-78°C
• Refractive Index: 1.3070
• GHS Hazard statements: H225-H314-H318
• European Hazard Symbols: Corrosive (C)
• European Hazard Symbols: Flammable (F)
• GHS Precautionary statements: P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 11-34
• Safety Statements: 16-26-33-36/37/39-45
• Storage Warning: Moisture Sensitive
• TSCA Listed: 是
• Hazard Class: 3
• UN Number: UN2924
• Packing Group: II

REFERENCES

• Esters of perfluoroalkyl carboxylic acids undergo Wittig reactions, for example with the ylide from (3-Phenylpropyl)triphenylphosphonium bromide, A12669, leading to 1-perfluoroalkyl enol ethers, which are useful precursors of various fluorinated derivatives: J. Org. Chem., 57, 3807 (1992); Org. Synth., 75, 153 (1997):
  
• Reagent for selective trifluoroacetylation of amines. Primary amines can be protected in the presence of secondary, and diamines selectively monoprotected. Primary amines can also be differentiated in terms of steric hindrance: Tetrahedron Lett., 36, 7357 (1995).