1,2-Bis(diphenylphosphino)ethane

• Catalog No.: A11419
• CAS Number: 1663-45-2
• M. F.: C26H24P2
• M. W.: 398.416282
• Purity: 97+%

SYNONYMS

• Title: 1,2-双(二苯基磷烷基)乙烷
• IUPAC name: [2-(diphenylphosphanyl)ethyl]diphenylphosphane
• IUPAC Traditional name: diphos
• Synonyms: Dppe; Diphos

DATABASE IDS

• MDL Number: MFCD00003047
• EC Number: 216-769-2
• Beilstein Number: 761261
• CAS Number: 1663-45-2

PROPERTIES

• Purity: 97+%
• Melting Point: 138-143°C
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P280G-P305+P351+P338
• Risk Statements: 36/37/38
• Safety Statements: 26-37
• Storage Warning: Air Sensitive
• TSCA Listed: 是

REFERENCES

• The catalyst prepared in situ with Sodium tetrachloropalladate(II) hydrate, 11886, catalyzes the carbonylation of allylic halides at atmospheric pressure: Chem. Lett., 1873 (1989):
  
• Useful replacement for Triphenylphosphine, L02502, in the Staudinger and Mitsunobu reactions, with the advantage of easier separation of the by-product bis(phosphine oxide) due to its higher polarity compared with triphenylphosphine oxide: Tetrahedron Lett., 39, 7787 (1998). Has also been used as an alternative to PPh₃ for the halodehydroxylation of alcohols, e.g. in combination with Hexachloroethane, L14297, alkyl chlorides are formed; the phosphine oxide by-product can readily be separated by filtration: Tetrahedron Lett., 42, 2459 (2001).
• Chelating phosphorus ligand.
• The complex with NiCl₂ catalyzes the coupling of haloaromatic compounds with Grignard reagents: J. Org. Chem.,49, 478 (1984).