4-Bromoveratrole

• Catalog No.: A11133
• CAS Number: 2859-78-1
• M. F.: C8H9BrO2
• M. W.: 217.05986
• Purity: 97%

SYNONYMS

• Title: 4-溴藜芦醚
• IUPAC name: 4-bromo-1,2-dimethoxybenzene
• IUPAC Traditional name: 4-bromo-1,2-dimethoxybenzene
• Synonyms: 4-Bromo-1,2-dimethoxybenzene; 3,4-Dimethoxybromobenzene

DATABASE IDS

• CAS Number: 2859-78-1
• Beilstein Number: 2046884
• MDL Number: MFCD00008381
• EC Number: 220-677-8

PROPERTIES

• Purity: 97%
• Boiling Point: 255-256°C
• Density: 1.510
• Flash Point: 109°C(228°F)
• Refractive Index: 1.5730
• TSCA Listed: 是

REFERENCES

• In the presence of sodamide, displacement by nucleophiles, e.g. anions of secondary amines or nitriles, occurs by an ortho-metallation-benzyne mechanism. The incoming nucleophile adds regioselectively such that the resulting anion is ortho-stabilized by methoxyl: J. Org. Chem., 48, 4397 (1983):
  
• The derived Grignard reagent has been used in the synthesis of the isoquinoline alkaloid (-)-mesembrine: J. Org. Chem., 60, 6785 (1995).