Ethyl L-lactate

• Catalog No.: A10900
• CAS Number: 687-47-8
• M. F.: C5H10O3
• M. W.: 118.1311
• Purity: 99%

SYNONYMS

• Title: L-乳酸乙酯
• IUPAC name: ethyl (2S)-2-hydroxypropanoate
• IUPAC Traditional name: ethyl lactate
• Synonyms: L-Lactic acid ethyl ester

DATABASE IDS

• CAS Number: 687-47-8
• Merck Index: 143817
• MDL Number: MFCD00065359
• EC Number: 211-694-1
• Beilstein Number: 1720839

PROPERTIES

• Purity: 99%
• Boiling Point: 152-155°C
• Density: 1.036
• Flash Point: 46°C(114°F)
• Melting Point: -25°C
• Optical Rotation: -11 (neat)
• Refractive Index: 1.4130
• GHS Hazard statements: H318-H226-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 10-37-41
• RTECS: OD5070000
• Safety Statements: 24-26-39
• TSCA Listed: 是
• Hazard Class: 3
• UN Number: UN1192
• Packing Group: III

REFERENCES

• Ethyl (or isobutyl) L-lactate adds to aryl methyl ketenes to give esters of 2-arylpropionic acids in which the chirality is transferred to the new chiral center to a surprising degree: J. Am. Chem. Soc., 111, 7650 (1989):
  
• Silylation followed by reaction with MeLi gives a useful chiral synthon. For preparation and discussion of reactivity, see: Org. Synth. Coll., 9, 139 (1998):
  
• For reaction with Diphenylphosphonic azide, A12124, in the prepartaion, with inversion, of ethyl (R)-2-azidopropionate, see: Org. Synth., 75, 31 (1997).