Pyridine hydrochloride

• Catalog No.: A10871
• CAS Number: 628-13-7
• M. F.: C5H6ClN
• M. W.: 115.56084
• Purity: 98%

SYNONYMS

• Title: 吡啶盐酸盐
• IUPAC name: pyridine hydrochloride
• IUPAC Traditional name: pyridine hydrochloride
• Synonyms: Pyridinium chloride

DATABASE IDS

• Beilstein Number: 3615340
• EC Number: 211-027-4
• MDL Number: MFCD00012802
• CAS Number: 628-13-7

PROPERTIES

• Purity: 98%
• Boiling Point: 222-224°C
• Melting Point: ca 145°C
• GHS Hazard statements: H302-H315-H319-H335
• European Hazard Symbols: X
• GHS Precautionary statements: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• Risk Statements: 22-36/37/38
• RTECS: UT4375000
• Safety Statements: 26-36/37-60
• Storage Warning: Hygroscopic
• TSCA Listed: 是

REFERENCES

• Demethylation of methyl aryl ethers can also be carried out under solvent-free conditions with microwave irradiation: J. Chem. Res. (Synop.), 394 (1999).
• Epoxides at ambient temperature in chloroform give chlorohydrins: Synth. Commun., 11, 287 (1981).
• In DMF, has been used for the conversion of alkyl tosylates to chlorides at room temperature: J. Am. Chem. Soc., 80, 2726 (1958).
• Cleaves N-trityl groups from histidine residues in peptide synthesis: Tetrahedron Lett., 28, 6031 (1987).
• Classical reagent for cleavage of aryl methyl ethers at 200-220 ^o : Ber ., 75, 445 (1942), avoiding the strongly acidic or basic conditions of some alternative methods; see, e.g.: J. Org. Chem., 27, 4660 (1962):
  
• Mild acid catalyst, e.g. in the formation of acetals with ethylene glycol: J. Org. Chem., 31, 26 (1966), or 1,3-propanediol: Bull. Soc. Chim. Fr., 2287 (1972); and in the Fischer indole synthesis for acid-sensitive substrates: Synthesis, 645 (1977).