3-Amino-4-methylpyridine

• Catalog No.: L19730
• CAS Number: 3430-27-1
• M. F.: C6H8N2
• M. W.: 108.14112
• Purity: 98%

SYNONYMS

• Title: 3-氨基-4-甲基吡啶
• IUPAC name: 4-methylpyridin-3-amine
• IUPAC Traditional name: 4-methylpyridin-3-amine
• Synonyms: 4-Methyl-3-pyridinamine; 3-Amino-4-picoline

DATABASE IDS

• Beilstein Number: 107792
• MDL Number: MFCD00128871
• CAS Number: 3430-27-1

PROPERTIES

• Purity: 98%
• Boiling Point: 254°C
• Melting Point: 102-106°C
• GHS Hazard statements: H301-H311-H315-H319-H335
• European Hazard Symbols: Toxic (T)
• GHS Precautionary statements: P280H-P305+P351+P338-P307+P311
• Risk Statements: 24/25-36/37/38
• Safety Statements: 26-36/37-45
• Storage Warning: Hygroscopic
• TSCA Listed: 否
• Hazard Class: 6.1
• UN Number: UN2811
• Packing Group: III

REFERENCES

• Ortho-lithiation with t-BuLi of the Boc-protected amine followed by addition of a Weinreb amide gave the 2-alkyl substituted 5-azaindole in good yield: J. Heterocycl. Chem., 29, 359 (1992), whereas DMF gave 6-azaindole in high yield: Synthesis, 877 (1996). 2-Substituted 6-azaindoles have also been synthesized in one step by direct dilithiation with s-BuLi, followed by reaction with an ester: J. Org, Chem., 70, 6512 (2005).