Home > Compound List > Product Information
Trifluoperazine_Molecular_structure_CAS_117-89-5)
Click picture or here to close

Trifluoperazine

Catalog No. DB00831 Name DrugBank
CAS Number 117-89-5 Website http://www.ualberta.ca/
M. F. C21H24F3N3S Telephone (780) 492-3111
M. W. 407.4955696 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 710

SYNONYMS

IUPAC name
10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine
IUPAC Traditional name
trifluoperazine
Brand Name
Stelazine
Novo-Trifluzine
Tryptazine
Triphtazine
Terfluzine
Eskazinyl
Fluoperazine
Modalina
Triflurin
Triftazine
Triphthasine
Triphthazine
Eskazine
Jatroneural
Stellazine
Synklor
Trazine
Triftazin
Triperazine
Triphtazin
Synonyms
Trifluoperazine Dihydrochloride
Trifluoromethylperazine
Trifluoroperazine
Triphthazine Dihydrochloride
Trifluperazine
Trifluoperazine HCl
Trifluoroperazine Hydrochloride
Trifluoroperazine Dihydrochloride
Trifluoperazine Hydrochloride
Tryptazine Dihydrochloride
Trifluoperazin
Trifluoperazina
Trifluroperizine

DATABASE IDS

PubChem SID 46507961
PubChem CID 5566
CAS Number 117-89-5

PROPERTIES

Hydrophobicity(logP) 4.9
Solubility 0.0122 mg/mL at 24 oC [YALKOWSKY,SH & DANNENFELSER,RM (1992)]

DETAILS

Description (English)
Item Information
Drug Groups approved
Description A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic. [PubChem]
Indication For the treatment of anxiety disorders, depressive symptoms secondary to anxiety and agitation.
Pharmacology Trifluoperazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Trifluoperazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Toxicity Symptoms of overdose include agitation, coma, convulsions, difficulty breathing, difficulty swallowing, dry mouth, extreme sleepiness, fever, intestinal blockage, irregular heart rate, low blood pressure, and restlessness.
Affected Organisms
Humans and other mammals
Biotransformation Hepatic.
Half Life 10-20 hours
External Links
Wikipedia
RxList
PDRhealth
Drugs.com

REFERENCES