Home > Compound List > Product Information
Tropicamide_Molecular_structure_CAS_1508-75-4)
Click picture or here to close

Tropicamide

Catalog No. DB00809 Name DrugBank
CAS Number 1508-75-4 Website http://www.ualberta.ca/
M. F. C17H20N2O2 Telephone (780) 492-3111
M. W. 284.3529 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 688

SYNONYMS

IUPAC name
N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide
IUPAC Traditional name
triaminic DM
Brand Name
Mydriafair
Mydriacyl
I-Picamide
Tropicacyl
Minims Tropicamide
Mydriaticum
Ocu-Tropic
Opticyl
Paremyd
Spectro-Cyl
Synonyms
Tropicamid

DATABASE IDS

PubChem SID 46505924
CAS Number 1508-75-4
PubChem CID 5593

PROPERTIES

Hydrophobicity(logP) 1.3

DETAILS

Description (English)
Item Information
Drug Groups approved
Description One of the muscarinic antagonists with pharmacologic action similar to atropine and used mainly as an ophthalmic parasympatholytic or mydriatic. [PubChem]
Indication Indicated to induce mydriasis (dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) in diagnostic procedures, such as measurement of refractive errors and examination of the fundus of the eye.
Pharmacology Tropicamide belongs to the group of medicines called anti-muscarinics. Tropicamide blocks the receptors in the muscles of the eye (muscarinic receptors). These receptors are involved controlling the pupil size and the shape of the lens. By blocking these receptors, tropicamide produces dilatation of the pupil (mydriasis) and prevents the eye from accommodating for near vision (cycloplegia). Tropicamide is given as eye drops to dilate the pupil and relax the lens so that eye examinations can be carried out thoroughly.
Toxicity Overdose can casue dry mouth, blurred vision, photophobia, hallucinations and rapid/irregular pulse.
Affected Organisms
Humans and other mammals
Protein Binding 45%
External Links
Wikipedia
Drugs.com

REFERENCES