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Halazepam

Catalog No. DB00801 Name DrugBank
CAS Number 23092-17-3 Website http://www.ualberta.ca/
M. F. C17H12ClF3N2O Telephone (780) 492-3111
M. W. 352.7381896 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 680

SYNONYMS

IUPAC name
7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one
IUPAC Traditional name
halazepam
Brand Name
Paxipam
Pacinone
Synonyms
Halazepamum [INN-Latin]

DATABASE IDS

PubChem CID 31640
PubChem SID 46508415
CAS Number 23092-17-3

PROPERTIES

Hydrophobicity(logP) 4.3

DETAILS

Description (English)
Item Information
Drug Groups illicit; approved
Description Halazepam is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a trifluoromethyl derivative of nordazepam. While its structure may be similar to chlordiazepoxide and diazepam, it has both less toxicity and less tendency to cause paradoxical hostility and aggression than either of them. [Wikipedia]
Indication Used to relieve anxiety, nervousness, and tension associated with anxiety disorders.
Affected Organisms
Humans and other mammals
Biotransformation Hepatic.
References
Fann WE, Pitts WM, Wheless JC: Pharmacology, efficacy, and adverse effects of halazepam, a new benzodiazepine. Pharmacotherapy. 1982 Mar-Apr;2(2):72-9. [Pubmed]
External Links
Wikipedia
Drugs.com

REFERENCES

  • Fann WE, Pitts WM, Wheless JC: Pharmacology, efficacy, and adverse effects of halazepam, a new benzodiazepine. Pharmacotherapy. 1982 Mar-Apr;2(2):72-9. Pubmed