Isothipendyl

• Catalog No.: DB08802
• CAS Number: 482-15-5
• M. F.: C16H19N3S
• M. W.: 285.40716

SYNONYMS

• IUPAC name: dimethyl(1-{9-thia-2,4-diazatricyclo[8.4.0.0^{3,8}]tetradeca-1(10),3,5,7,11,13-hexaen-2-yl}propan-2-yl)amine
• IUPAC Traditional name: isothipendyl
• Brand Name: Andanton; Actapront; Udantol; Odantol; Nilergex
• Synonyms: Isothipendylum

DATABASE IDS

• CAS Number: 482-15-5

DETAILS

Description (English)

• Drug Groups: approved
• Description: Isothipendyl is an antihistamine and anticholinergic used as an antipruritic.
• Indication: For the topical treatment of itching associated with allergic reactions.
• Pharmacology: Isothipendyl, an azaphenothiazine derivative, competitively binds to histamine (H1) receptors, resulting in inhibition of the pharmacological effects of histamines. It also has some sedative, anticholinergic and antiserotoninergic effects.
• Affected Organisms: Humans and other mammals
• References: Moreau A, Dompmartin A, Dubreuil A, Leroy D: Phototoxic and photoprotective effects of topical isothipendyl. Photodermatol Photoimmunol Photomed. 1995 Apr;11(2):50-4. [Pubmed]
• External Links: Wikipedia

REFERENCES

• Moreau A, Dompmartin A, Dubreuil A, Leroy D: Phototoxic and photoprotective effects of topical isothipendyl. Photodermatol Photoimmunol Photomed. 1995 Apr;11(2):50-4. Pubmed