Antazoline

• Catalog No.: DB08799
• CAS Number: 91-75-8
• M. F.: C17H19N3
• M. W.: 265.35286

SYNONYMS

• IUPAC name: N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline
• IUPAC Traditional name: antazoline
• Brand Name: Histostab; Antistin; Antasten; Antihistal; Antastan
• Synonyms: Phenazolin; Phenazoline

DATABASE IDS

• CAS Number: 91-75-8

DETAILS

Description (English)

• Drug Groups: approved
• Description: Antazoline is a 1st generation antihistamine that also anticholinergic properties used to relieve nasal congestion and in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis.
• Indication: Used to relieve nasal congestion and in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis.
• Pharmacology: Antazoline is a histamine H1 receptor antagonist. It selectively bind to but does not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
• Affected Organisms: Humans and other mammals
• References: Figus M, Fogagnolo P, Lazzeri S, Capizzi F, Romagnoli M, Canovetti A, Iester M, Ferreras A, Rossetti L, Nardi M: Treatment of allergic conjunctivitis: results of a 1-month, single-masked randomized study. Eur J Ophthalmol. 2010 Sep-Oct;20(5):811-8. [Pubmed]
• External Links: Wikipedia

REFERENCES

• Figus M, Fogagnolo P, Lazzeri S, Capizzi F, Romagnoli M, Canovetti A, Iester M, Ferreras A, Rossetti L, Nardi M: Treatment of allergic conjunctivitis: results of a 1-month, single-masked randomized study. Eur J Ophthalmol. 2010 Sep-Oct;20(5):811-8. Pubmed