| Item |
Information |
|
Drug Groups
|
approved |
|
Description
|
Diphemanil Methylsulfate is a quaternary ammonium anticholinergic. It binds muscarinic acetycholine receptors and thereby decreases secretory excretion of stomach acids as well as saliva and sweat. |
| Indication |
Used in the treatment of peptic ulcer, gastric hyperacidity, and hypermotility in gastritis and pylorospasm, and in the treatment of hyperhidrosis (excessive perspiration). |
| Pharmacology |
Diphemanil Methylsulfate is a quaternary ammonium anticholinergic. It binds muscarinic acetycholine receptors and thereby decreases secretory excretion of stomach acids as well as saliva and sweat. |
| Affected Organisms |
| • |
Humans and other mammals |
|
| Absorption |
Poorly absorbed from the gastrointestinal tract with an absolute bioavailability of 15 to 25%. |