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Pirenzepine

Catalog No. DB00670 Name DrugBank
CAS Number 28797-61-7 Website http://www.ualberta.ca/
M. F. C19H21N5O2 Telephone (780) 492-3111
M. W. 351.40234 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 552

SYNONYMS

IUPAC name
2-[2-(4-methylpiperazin-1-yl)acetyl]-2,4,9-triazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10-one
IUPAC Traditional name
pirenzepine
Brand Name
Pirenzepin
Pirenzepinum [INN-Latin]
Tabe
Pirenzepine Gastrozepin
Bisvanil
Gasteril
Gastrozepin
Leblon
Pirenzepina [INN-Spanish]
Ulcosan

DATABASE IDS

CAS Number 28797-61-7
PubChem SID 46509029
PubChem CID 4848

PROPERTIES

Hydrophobicity(logP) 0.6

DETAILS

Description (English)
Item Information
Drug Groups approved
Description An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as cimetidine and ranitidine. It is generally well tolerated by patients. [PubChem]
Indication For the treatment of peptic ulcer, gastric ulcer, and duodenal ulcer.
Pharmacology Pirenzepine belongs to a group of medications called antispasmodics/anticholinergics. These medications are used to relieve cramps or spasms of the stomach, intestines, and bladder. Pirenzepine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be used to prevent nausea, vomiting, and motion sickness.
Affected Organisms
Humans and other mammals
References
Czepita D: [Fundamentals of modern treatment of myopia] Ann Acad Med Stetin. 2005;51(2):5-9. [Pubmed]
External Links
Wikipedia

REFERENCES

  • Czepita D: [Fundamentals of modern treatment of myopia] Ann Acad Med Stetin. 2005;51(2):5-9. Pubmed