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L-Isoleucine

Catalog No. DB00167 Name DrugBank
CAS Number 73-32-5 Website http://www.ualberta.ca/
M. F. C6H13NO2 Telephone (780) 492-3111
M. W. 131.17292 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 52

SYNONYMS

IUPAC name
(2S,3S)-2-amino-3-methylpentanoic acid
IUPAC Traditional name
L-isoleucine
Synonyms
(2S,3S)-a-Amino-b-methylvaleric acid
L-(+)-Isoleucine
Isoleucine
erythro-L-Isoleucine
2S,3S-Isoleucine
(2S,3S)-2-Amino-3-methylpentanoic acid
(2S,3S)-a-Amino-b-methyl-n-valeric acid
(S)-Isoleucine
(S,S)-Isoleucine
2-Amino-3-methylvaleric acid
L-Ile

DATABASE IDS

PubChem CID 6306
PubChem SID 46506864
CAS Number 73-32-5

PROPERTIES

Hydrophobicity(logP) -1.6
Solubility 34.4 mg/mL at 25 oC [YALKOWSKY,SH & DANNENFELSER,RM (1992)]

DETAILS

Description (English)
Item Information
Drug Groups approved; nutraceutical
Description An essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of leucine. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels. [PubChem]
Indication The branched-chain amino acids may have antihepatic encephalopathy activity in some. They may also have anticatabolic and antitardive dyskinesia activity.
Pharmacology They provide ingredients for the manufacturing of other essential biochemical components in the body, some of which are utilized for the production of energy, stimulants to the upper brain and helping you to be more alert.
Toxicity Symptoms of hypoglycemia, increased mortality in ALS patients taking large doses of BCAAs
Affected Organisms
Humans and other mammals
Biotransformation Hepatic
Absorption Absorbed from the small intestine by a sodium-dependent active-transport process
External Links
PDRhealth

REFERENCES