| Item |
Information |
|
Drug Groups
|
approved |
|
Description
|
An alpha-2 selective adrenergic agonist used as an antihypertensive agent. [PubChem] |
| Indication |
For management of High blood pressure |
| Pharmacology |
Guanabenz, a centrally acting α-2 adrenergic agonist, is indicated for treatment of hypertension. |
| Toxicity |
Excessive contraction of the pupils, irritability, low blood pressure, sleepiness, slow heartbeat, sluggishness |
| Affected Organisms |
| • |
Humans and other mammals |
|
| Biotransformation |
Hepatic |
| Absorption |
Approximately 75% absorbed from gastrointestinal tract |
| Half Life |
6 hours. |
| Protein Binding |
90% |
| External Links |
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