Monobenzone

• Catalog No.: DB00600
• CAS Number: 103-16-2
• M. F.: C13H12O2
• M. W.: 200.23318

SYNONYMS

• IUPAC name: 4-(benzyloxy)phenol
• IUPAC Traditional name: monobenzone
• Brand Name: Carmifal; Agerite; Alba; Alba-Dome; Depigman; Dermochinona; Leucodinine; Monobenzon; Pigmex; Superlite; AgeRite Alba; Benoquin
• Synonyms: Hydroquinone benzyl ether; p-Hydroxyphenyl benzyl ether; Benzoquin; Monobenzyl ether hydroquinone; Monobenzyl hydroquinone; Hydrochinon monobenzylether [Czech]; Hydroquinone monobenzyl ether; Benzyl p-hydroxyphenyl ether; Benzyl hydroquinone; Monobenzona [INN-Spanish]; Monobenzone [INN]; Monobenzonum [INN-Latin]; Monobenzyl Ether of Hydroquinone

DATABASE IDS

• CAS Number: 103-16-2
• PubChem SID: 46507466
• PubChem CID: 7638

PROPERTIES

• Hydrophobicity(logP): 3.2
• Solubility: 251 mg/L

DETAILS

Description (English)

• Drug Groups: approved
• Description: Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water.; ; The topical application of monobenzone in animals increases the excretion of melanin from the melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes and permanent depigmentation.
• Indication: Used topically to treat the loss of skin color (vitiligo).
• Pharmacology: Monobenzone is the monobenzyl ether of hydroquinone. Monobenzone, applied topically to the skin, is used as a depigmenting agent inhibitting melanin produced by polymerization of oxidation products of tyrosine and dihydroxyphenyl compounds. Monobenzone works by permanently removing color from normal skin located around skin with vitiligo.
• Affected Organisms: Humans and other mammals
• External Links: Wikipedia; Drugs.com