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Cinalukast

Catalog No. DB00587 Name DrugBank
CAS Number 128312-51-6 Website http://www.ualberta.ca/
M. F. C23H28N2O3S Telephone (780) 492-3111
M. W. 412.54502 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 469

SYNONYMS

IUPAC name
3-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}carbamoyl)-2,2-diethylpropanoic acid
IUPAC Traditional name
@cinalukast
Brand Name
Cinalukast [Usan:Inn]

DATABASE IDS

PubChem SID 46505799
CAS Number 128312-51-6
PubChem CID 6436135

PROPERTIES

Hydrophobicity(logP) 4

DETAILS

Description (English)
Item Information
Drug Groups approved
Description Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Cinalukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.
Indication For Protection against second- phase inflamation in exercise-induced bronchoconstriction and Asthma.
Pharmacology Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Cinalukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.
Affected Organisms
Humans and other mammals

REFERENCES