Home > Compound List > Product Information
Udenafil_Molecular_structure_CAS_268203-93-6)
Click picture or here to close

Udenafil

Catalog No. DB06267 Name DrugBank
CAS Number 268203-93-6 Website http://www.ualberta.ca/
M. F. C25H36N6O4S Telephone (780) 492-3111
M. W. 516.65614 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 4423

SYNONYMS

IUPAC name
3-{1-methyl-7-oxo-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin-5-yl}-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-4-propoxybenzene-1-sulfonamide
IUPAC Traditional name
@udenafil
Brand Name
Zydena

DATABASE IDS

CAS Number 268203-93-6
PubChem SID 99443240
PubChem CID 6918523

PROPERTIES

DETAILS

Description (English)
Item Information
Drug Groups approved; investigational
Description Udenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It has been approved in South Korea and will be marketed under the brand name Zydena. It is not yet approved for use in the U.S., E.U., or Canada.
Indication Investigated for use/treatment in erectile dysfunction and hypertension.
Pharmacology Udenafil is a potent selective phosphodiesterase type 5 (PDE5) inhibitor.
Affected Organisms
Humans and other mammals
Biotransformation Hepatic. Metabolized by CYP3A4 and CYP3A5.
References
Ji HY, Shim HJ, Yoo M, Park ES, Lee HS: Transport of a new erectogenic udenafil in Caco-2 cells. Arch Pharm Res. 2007 Sep;30(9):1168-73. [Pubmed]
Ku HY, Ahn HJ, Seo KA, Kim H, Oh M, Bae SK, Shin JG, Shon JH, Liu KH: The contributions of cytochromes P450 3A4 and 3A5 to the metabolism of the phosphodiesterase type 5 inhibitors sildenafil, udenafil, and vardenafil. Drug Metab Dispos. 2008 Jun;36(6):986-90. Epub 2008 Feb 28. [Pubmed]
External Links
Wikipedia

REFERENCES

  • Ji HY, Shim HJ, Yoo M, Park ES, Lee HS: Transport of a new erectogenic udenafil in Caco-2 cells. Arch Pharm Res. 2007 Sep;30(9):1168-73. Pubmed
  • Ku HY, Ahn HJ, Seo KA, Kim H, Oh M, Bae SK, Shin JG, Shon JH, Liu KH: The contributions of cytochromes P450 3A4 and 3A5 to the metabolism of the phosphodiesterase type 5 inhibitors sildenafil, udenafil, and vardenafil. Drug Metab Dispos. 2008 Jun;36(6):986-90. Epub 2008 Feb 28. Pubmed