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Ecabet

Catalog No. DB05265 Name DrugBank
CAS Number 86408-72-2 Website http://www.ualberta.ca/
M. F. C20H28O5S Telephone (780) 492-3111
M. W. 380.49832 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 4410

SYNONYMS

IUPAC name
(1R,4aS,10aR)-1,4a-dimethyl-7-(propan-2-yl)-6-sulfo-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid
IUPAC Traditional name
ecabet
Brand Name
Gastrom
Synonyms
Ecabetum
Ecabetum [inn-latin]
Ecabet [inn]
ecabet sodium
12-sulfodehydroabietic acid
13-Isopropyl-12-sulfopodocarpa-8,11,13-trien-15-oic acid
Ecabet (inn)

DATABASE IDS

PubChem SID 99443230
PubChem CID 65781
CAS Number 86408-72-2

PROPERTIES

DETAILS

Description (English)
Item Information
Drug Groups approved; investigational
Description Ecabet is a prescription eye drop for the treatment of dry eye syndrome. Ecabet represents a new class of molecules that increases the quantity and quality of mucin produced by conjunctival goblet cells and corneal epithelia. Mucin is a glycoprotein component of tear film that lubricates while retarding moisture loss from tear evaporation. Ecabet is currently marketed in Japan as an oral agent for treatment of gastric ulcers and gastritis.
Indication For the treatment of reflux oesophagitis and peptic ulcer disease.
External Links
Drugs.com

REFERENCES