Fluspirilene

• Catalog No.: DB04842
• CAS Number: 1841-19-6
• M. F.: C29H31F2N3O
• M. W.: 475.5727464

SYNONYMS

• IUPAC name: 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
• IUPAC Traditional name: imap
• Brand Name: Redeptin; Imap; Lopac-F-100
• Synonyms: Fluspirileno [inn-spanish]; Fluspirilenum [inn-latin]

DATABASE IDS

• PubChem CID: 3396
• PubChem SID: 46508202
• CAS Number: 1841-19-6

PROPERTIES

• Hydrophobicity(logP): 5.86 [HANSCH,C ET AL. (1995)]
• Solubility: 0.01 mg/mL at 25 oC [MERCK INDEX (1996)]

DETAILS

Description (English)

• Drug Groups: approved
• Description: A long-acting injectable antipsychotic agent used for chronic schizophrenia.
• Indication: Used for the treatment of schizophrenia.
• Pharmacology: Fluspirilene is a relatively long-acting injectable depot antipsychotic drug used for schizophrenia. Fluspirilene does not differ greatly from other depot antipsychotics (fluphenazine decanoate, fluphenazine enathate, perphenazine onanthat, pipotiazine undecylenate) with respect to treatment efficacy, response or tolerability. Outcomes suggest that fluspirilene does not differ significantly from oral antipsychotics or in different weekly regimens, although much cannot be inferred because of the shortage of trials.
• Affected Organisms: Humans and other mammals
• External Links: Wikipedia