Home > Compound List > Product Information
Lysergic Acid Diethylamide_Molecular_structure_CAS_50-37-3)
Click picture or here to close

Lysergic Acid Diethylamide

Catalog No. DB04829 Name DrugBank
CAS Number 50-37-3 Website http://www.ualberta.ca/
M. F. C20H25N3O Telephone (780) 492-3111
M. W. 323.432 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 4373

SYNONYMS

IUPAC name
(4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene-4-carboxamide
IUPAC Traditional name
lysergic acid diethylamide
Synonyms
Blotter acid
Lysergide
Orange sunshine
N,n-diethyllysergamide
Brown dots
n,n-diethyl-(+)-lysergamide
Lysergidum [inn-latin]
Delysid
D-lysergic acid diethylamide
Cubes
Mellow yellow
Lysergic acid amide
Lysergamid
Frogs
Domes
LSD-25
Paper acid
N,n-diethyl-d-lysergamide
D-lysergic acid n,n-diethylamide
D-LSD-25
D-LSD
Cupcakes
Coffeinum
Lysergaure diethylamid
Lysergamide
Lucy in the sky with diamonds
Heavenly blue
Gelatin chips
(+)-LSD
9,10-Didehydro-N,N-diethyl-6-methylergoline-8b-carboxamide
Bart simpson
Big f
Blue cheer
Wedges
Wedding bells
Trippers
TMA
The hawk
Sunshine
Sugar
Strawberry fields
Spoonies
N,N-Diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide
Diethylamid kyseliny lysergove [czech]
Dextrolysergic acid diethylamide
D-lysergic acid dethylamide
Contact lens
Clearlight
Chocolate chips
Chief
Cherry top
California sunshine
Blue star
Blue mist
Microdots
Mean green
Lysergic acid diethylamide-25
Greenies
Flats
Fifty
Ergine
LSD
(+)-lysergic acid diethylamide
Acid
Barrels
Bartman
Beast
Blue acid
ZEN
Yellows
Window pane
White light
Ubergluben
TABS
Sugar lump
Scapes
Royal blue
Purple microdot
Purple haze
Pearly gates
Owsley
Orange wedges
Orange mushroom

DATABASE IDS

PubChem SID 46506397
PubChem CID 5761
CAS Number 50-37-3

PROPERTIES

Hydrophobicity(logP) 2.95 [HANSCH,C ET AL. (1995)]

DETAILS

Description (English)
Item Information
Drug Groups illicit; withdrawn
Description Debate continues over the nature and causes of chronic flashbacks. Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by experimental evidence. Some say HPPD is a manifestation of post-traumatic stress disorder, not related to the direct action of LSD on brain chemistry, and varies according to the susceptibility of the individual to the disorder. Many emotionally intense experiences can lead to flashbacks when a person is reminded acutely of the original experience. However, not all published case reports of chronic flashbacks appear to describe an anxious hyper-vigilant state reminiscent of post-traumatic stress disorder.
Toxicity Estimates for the lethal dosage (LD50) of LSD range from 200 μg/kg to more than 1 mg/kg of human body mass, though most sources report that there are no known human cases of such an overdose.
Affected Organisms
Humans and other mammals
Biotransformation Hepatic.
Half Life 3 hours
References
GREINER T, BURCH NR, EDELBERG R: Psychopathology and psychophysiology of minimal LSD-25 dosage; a preliminary dosage-response spectrum. AMA Arch Neurol Psychiatry. 1958 Feb;79(2):208-10. [Pubmed]
AGHAJANIAN GK, BING OH: PERSISTENCE OF LYSERGIC ACID DIETHYLAMIDE IN THE PLASMA OF HUMAN SUBJECTS. Clin Pharmacol Ther. 1964 Sep-Oct;5:611-4. [Pubmed]
Papac DI, Foltz RL: Measurement of lysergic acid diethylamide (LSD) in human plasma by gas chromatography/negative ion chemical ionization mass spectrometry. J Anal Toxicol. 1990 May-Jun;14(3):189-90. [Pubmed]
Nichols DE: Hallucinogens. Pharmacol Ther. 2004 Feb;101(2):131-81. [Pubmed]
Jacobs BL, Heym J, Rasmussen K: Raphe neurons: firing rate correlates with size of drug response. Eur J Pharmacol. 1983 Jun 3;90(2-3):275-8. [Pubmed]
External Links
Wikipedia

REFERENCES

  • GREINER T, BURCH NR, EDELBERG R: Psychopathology and psychophysiology of minimal LSD-25 dosage; a preliminary dosage-response spectrum. AMA Arch Neurol Psychiatry. 1958 Feb;79(2):208-10. Pubmed
  • AGHAJANIAN GK, BING OH: PERSISTENCE OF LYSERGIC ACID DIETHYLAMIDE IN THE PLASMA OF HUMAN SUBJECTS. Clin Pharmacol Ther. 1964 Sep-Oct;5:611-4. Pubmed
  • Papac DI, Foltz RL: Measurement of lysergic acid diethylamide (LSD) in human plasma by gas chromatography/negative ion chemical ionization mass spectrometry. J Anal Toxicol. 1990 May-Jun;14(3):189-90. Pubmed
  • Jacobs BL, Heym J, Rasmussen K: Raphe neurons: firing rate correlates with size of drug response. Eur J Pharmacol. 1983 Jun 3;90(2-3):275-8. Pubmed
  • Nichols DE: Hallucinogens. Pharmacol Ther. 2004 Feb;101(2):131-81. Pubmed