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Thenoyltrifluoroacetone_Molecular_structure_CAS_326-91-0)
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Thenoyltrifluoroacetone

Catalog No. DB04795 Name DrugBank
CAS Number 326-91-0 Website http://www.ualberta.ca/
M. F. C8H5F3O2S Telephone (780) 492-3111
M. W. 222.1843096 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 4341

SYNONYMS

IUPAC name
4,4,4-trifluoro-1-(thiophen-2-yl)butane-1,3-dione
IUPAC Traditional name
thenoyltrifluoroacetone
Synonyms
Perfluoroacetyl(2-thenoyl)methane
1,1,1-Trifluoro-3-(2-thenoyl)acetone
.alpha.-Thenoyltrifluoroacetone
2-Thenoyltrifluoroacetone
alpha-Thenoyltrifluoroacetone
1-Thenoyl-3,3,3-trifluoroacetone
TTFA

DATABASE IDS

CAS Number 326-91-0
PubChem SID 46504456
PubChem CID 5601

PROPERTIES

Hydrophobicity(logP) 1.46 [HANSCH,C ET AL. (1995)]

DETAILS

Description (English)
Item Information
Drug Groups experimental
Description Thenoyltrifluoroacetone is a chelating agent and inhibitor of cellular respiration. [PubChem]
Pharmacology Studies indicate that thenoyltrifluoroacetone is a potent inhibitor of carboxylesterase activity, in addition to its ability to inhibit mitochondrial complex II activity.
Affected Organisms
Humans and other mammals
References
Zhang JG, Fariss MW: Thenoyltrifluoroacetone, a potent inhibitor of carboxylesterase activity. Biochem Pharmacol. 2002 Feb 15;63(4):751-4. [Pubmed]

REFERENCES

  • Zhang JG, Fariss MW: Thenoyltrifluoroacetone, a potent inhibitor of carboxylesterase activity. Biochem Pharmacol. 2002 Feb 15;63(4):751-4. Pubmed