Streptolydigin

• Catalog No.: DB04785
• CAS Number: 7229-50-7
• M. F.: C32H44N2O9
• M. W.: 600.69976

SYNONYMS

• IUPAC name: (2S)-2-[(2S)-4-[(2E,4E,6R)-6-[(1S,2S,5S,6S,7S)-1,6-dimethyl-8,9-dioxaspiro[bicyclo[3.3.1]nonane-2,2'-oxiran]-3-en-7-yl]-4-methylhepta-2,4-dienoyl]-5-hydroxy-1-[(2S,5S,6S)-5-hydroxy-6-methyloxan-2-yl]-3-oxo-2,3-dihydro-1H-pyrrol-2-yl]-N-methylpropanamide
• IUPAC Traditional name: streptolydigin
• Synonyms: Antibiotic D-45; Portamycin

DATABASE IDS

• PubChem SID: 46505558
• PubChem CID: 6436180
• CAS Number: 7229-50-7

DETAILS

Description (English)

• Drug Groups: experimental
• Pharmacology: Streptolydigin is an antibiotic which works by blocking nucleic acid chain elongation by binding to the polymerase, thus stopping RNA polymerase activity inside a cell. Specifically, it inhibits the assembly of the RNA polymerase II transcription complex and DNA polymerase III transcription. It is active against a number of gram positive bacteria.
• Affected Organisms: Enteric bacteria and other eubacteria
• External Links: Wikipedia