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Aniracetam

Catalog No. DB04599 Name DrugBank
CAS Number 72432-10-1 Website http://www.ualberta.ca/
M. F. C12H13NO3 Telephone (780) 492-3111
M. W. 219.23652 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 4164

SYNONYMS

IUPAC name
1-(4-methoxybenzoyl)pyrrolidin-2-one
IUPAC Traditional name
1-(4-methoxybenzoyl)pyrrolidin-2-one
Brand Name
Sarpul
Draganon
AMPAMET
Synonyms
1-P-ANISOYL-2-PYRROLIDINONE

DATABASE IDS

CAS Number 72432-10-1
PubChem CID 2196
PubChem SID 46506607

PROPERTIES

DETAILS

Description (English)
Item Information
Drug Groups experimental
Description Compound with anti-depressive properties used as a mental performance enhancer.
Pharmacology Aniracetam possesses a wide range of anxiolytic properties, which may be mediated by an interaction between cholinergic, dopaminergic and serotonergic systems.
Affected Organisms
Humans and other mammals
Half Life 1-2.5 hours
References
Nakamura K, Kurasawa M: Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. Eur J Pharmacol. 2001 May 18;420(1):33-43. [Pubmed]
Lawrence JJ, Brenowitz S, Trussell LO: The mechanism of action of aniracetam at synaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors: indirect and direct effects on desensitization. Mol Pharmacol. 2003 Aug;64(2):269-78. [Pubmed]
External Links
Wikipedia

REFERENCES

  • Nakamura K, Kurasawa M: Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. Eur J Pharmacol. 2001 May 18;420(1):33-43. Pubmed
  • Lawrence JJ, Brenowitz S, Trussell LO: The mechanism of action of aniracetam at synaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors: indirect and direct effects on desensitization. Mol Pharmacol. 2003 Aug;64(2):269-78. Pubmed