1-benzylimidazole

• Catalog No.: DB04581
• CAS Number: 4238-71-5
• M. F.: C10H10N2
• M. W.: 158.1998

SYNONYMS

• IUPAC name: 1-benzyl-1H-imidazole
• IUPAC Traditional name: 1-benzylimidazole
• Synonyms: N-Benzylimidazole; BIM; 1-Benzyl-1H-imidazole

DATABASE IDS

• PubChem SID: 46506844
• PubChem CID: 77918
• CAS Number: 4238-71-5

PROPERTIES

• Hydrophobicity(logP): 1.60 [AVDEEF,A (1993)]

DETAILS

Description (English)

• Drug Groups: experimental
• Description: 1-benzylimidazole, an N-imidazole derivative, has been shown to have strong cardiotonic activity.
• Affected Organisms: Humans and other mammals
• References: Mori Y, Iimura K, Hirano K: N-benzylimidazole, a potent inducer of rat liver enzymes involved in mutagenic activation of various carcinogens. Mutat Res. 1993 Jun;302(2):129-33. [Pubmed] ; Lucas J, Chan PS, Mateja N, Cervoni P, Ronsberg MA, Lipchuck LM: 1-Benzylimidazole, a thromboxane synthetase inhibitor acutely lowers blood pressure mainly by alpha-adrenoceptor blockade in spontaneously hypertensive rats (SHR). Prostaglandins Leukot Med. 1983 Dec;12(4):409-21. [Pubmed] ; Tuttle RS, Garcia-Minor C, Simon M: Cardiovascular effects of 1-benzylimidazole. J Pharmacol Exp Ther. 1975 Sep;194(3):624-32. [Pubmed]

REFERENCES

• Mori Y, Iimura K, Hirano K: N-benzylimidazole, a potent inducer of rat liver enzymes involved in mutagenic activation of various carcinogens. Mutat Res. 1993 Jun;302(2):129-33. Pubmed
• Lucas J, Chan PS, Mateja N, Cervoni P, Ronsberg MA, Lipchuck LM: 1-Benzylimidazole, a thromboxane synthetase inhibitor acutely lowers blood pressure mainly by alpha-adrenoceptor blockade in spontaneously hypertensive rats (SHR). Prostaglandins Leukot Med. 1983 Dec;12(4):409-21. Pubmed
• Tuttle RS, Garcia-Minor C, Simon M: Cardiovascular effects of 1-benzylimidazole. J Pharmacol Exp Ther. 1975 Sep;194(3):624-32. Pubmed