Gadoversetamide

• Catalog No.: DB00538
• CAS Number: 131069-91-5
• M. F.: C20H34GdN5O10
• M. W.: 661.76146

SYNONYMS

• IUPAC name: gadolinium(3+) ion 2-[bis({2-[(carboxylatomethyl)({[(2-methoxyethyl)carbamoyl]methyl})amino]ethyl})amino]acetate
• IUPAC Traditional name: gadolinium(3+) 2-[bis({2-[(carboxylatomethyl)({[(2-methoxyethyl)carbamoyl]methyl})amino]ethyl})amino]acetate
• Brand Name: OptiMARK
• Synonyms: Gadoversetamide [USAN:INN:BAN]; gadoversetamide

DATABASE IDS

• CAS Number: 131069-91-5
• PubChem SID: 46504481
• PubChem CID: 444013

DETAILS

Description (English)

• Drug Groups: approved; investigational
• Description: Gadoversetamide is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver. It is marketed under the trade name OptiMARK.
• Indication: Gadoversetamide is an MRI contrast agent used for MRI diagnostic procedures to provide increased enhancement and visualization of lesions of the brain, spine and liver, including tumors.
• Affected Organisms: Humans and other mammals
• Biotransformation: None detected
• Half Life: Distribution 13.3 ± 6.8 (mean) minutes, elimination 103.6 ± 19.5 (mean) minutes.
• Elimination: The mean cumulative urinary excretion of gadoversetamide at 72 hours was approximately 93.5% for renal impaired patients and 95.8% for subjects with normal renal function
• Distribution: * 162 ± 25 mL/kg [normal subjects]
• Clearance: * 72 +/- 16.3 mL/hr/kg [healthy]
• External Links: Wikipedia