Zosuquidar Trihydrochloride

• Catalog No.: Z700870
• CAS Number: 167465-36-3
• M. F.: C32H31F2N3O2
• M. W.: 527.6042464
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2R)-1-{4-[(2R,4S,11R)-3,3-difluorotetracyclo[10.4.0.0^2,^4.0^5,^1^0]hexadeca-1(12),5(10),6,8,13,15-hexaen-11-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol
• IUPAC Traditional name: (2R)-1-{4-[(2R,4S,11R)-3,3-difluorotetracyclo[10.4.0.0^2,^4.0^5,^1^0]hexadeca-1(12),5(10),6,8,13,15-hexaen-11-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol
• Synonyms: (αR)-4-[(1aα,6α,10bα)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]-α-[(5-quinolinyloxy)methyl]-1-piperazineethanol Hydrochloride; LY 335979; RS 33295-198; Zosuquidar Hydrochloride

DATABASE IDS

• CAS Number: 167465-36-3

PROPERTIES

• Apperance: Pale Yellow Solid
• Melting Point: 172-176°C
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Multi-drug resistance (MDR) modulator; selective inhibitor of P-glycoprotein (P-gp). Antineoplastic adjunct (chemosensitizer).

REFERENCES

• Green, L.J., et al.: Biochem. Pharmacol., 61, 1393 (2001)
• Shepard, R.L., et al.: Int. J. Cancer, 103, 121 (2001)