ZK-994

• Catalog No.: Z485900
• CAS Number: 686773-12-6
• M. F.: C21H22FNaO7
• M. W.: 428.3833532

SYNONYMS

• IUPAC name: sodium 2-{[(2S,3R,4E,6E,10E,12S)-13-(4-fluorophenoxy)-2,3,12-trihydroxytrideca-4,6,10-trien-8-yn-1-yl]oxy}acetate
• IUPAC Traditional name: sodium 2-{[(2S,3R,4E,6E,10E,12S)-13-(4-fluorophenoxy)-2,3,12-trihydroxytrideca-4,6,10-trien-8-yn-1-yl]oxy}acetate
• Synonyms: ZK-192; 2-[[(2S,3R,4E,6E,10E,12S)-13-(4-Fluorophenoxy)-2,3,12-trihydroxy-4,6,10-tridecatrien-8-yn-1-yl]oxy]acetic Acid Sodium Salt

DATABASE IDS

• CAS Number: 686773-12-6

DETAILS

Description (English)

ZK-994 is a β-oxidation-resistant lipoxin A4 receptor agonist. ZK-994 is used to treat hapten-induced colitis by attenuating inflammation and immune dysfunction.

REFERENCES

• Fiorucci, S. et al.: Proc. Nat. Acad. Sci. USA, 101, 15736 (2004)
• Levy, B.D. et al.: FASEB J., 21, 3877 (2004)