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Zaprinast

Catalog No. Z150000 Name Toronto Research Chemicals
CAS Number 37762-06-4 Website http://www.trc-canada.com
M. F. C13H13N5O2 Telephone +1 (416) 665-9696
M. W. 271.27462 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 179627

SYNONYMS

IUPAC name
5-(2-propoxyphenyl)-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
IUPAC Traditional name
5-(2-propoxyphenyl)-3H,6H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
Synonyms
3,6-dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one
M&B 22,948
1,4-Dihydro-5-[2-propoxyphenyl]-7H-1,2,3-triazolo[4,5-d]pyrimidine-7-one
8-Aza-2-(2-propoxyphenyl)-6-purinone

DATABASE IDS

CAS Number 37762-06-4

PROPERTIES

Certificate of Analysis Download
Apperance Pale Pink Solid
Melting Point 237-238°C dec.
Solubility DMSO
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
A selective inhibitor of cyclic-GMP phosphodiesterase (PDE V, calmodulin insensitive). Since cGMP mediates the vasorelaxant action of nitric oxide, as well as the natriuretic and diuretic effect of atrial natriuretic factor (ANF) through the activation of

REFERENCES

  • Burns, F., et al.: Biochem. J., 238, 487 (1992)
  • Lugnier, C., et al.: Am. J. Physiol., 262, H654 (1992)