Zaprinast

• Catalog No.: Z150000
• CAS Number: 37762-06-4
• M. F.: C13H13N5O2
• M. W.: 271.27462
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 5-(2-propoxyphenyl)-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
• IUPAC Traditional name: 5-(2-propoxyphenyl)-3H,6H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
• Synonyms: 3,6-dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one; M&B 22,948; 1,4-Dihydro-5-[2-propoxyphenyl]-7H-1,2,3-triazolo[4,5-d]pyrimidine-7-one; 8-Aza-2-(2-propoxyphenyl)-6-purinone

DATABASE IDS

• CAS Number: 37762-06-4

PROPERTIES

• Apperance: Pale Pink Solid
• Melting Point: 237-238°C dec.
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A selective inhibitor of cyclic-GMP phosphodiesterase (PDE V, calmodulin insensitive). Since cGMP mediates the vasorelaxant action of nitric oxide, as well as the natriuretic and diuretic effect of atrial natriuretic factor (ANF) through the activation of

REFERENCES

• Burns, F., et al.: Biochem. J., 238, 487 (1992)
• Lugnier, C., et al.: Am. J. Physiol., 262, H654 (1992)