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Zileuton-d4 (major)

Catalog No. Z420002 Name Toronto Research Chemicals
CAS Number 1189878-76-9 Website http://www.trc-canada.com
M. F. C11H12N2O2S Telephone +1 (416) 665-9696
M. W. 236.29018 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 179577

SYNONYMS

IUPAC name
1-[1-(1-benzothiophen-2-yl)(2H4)ethyl]-1-hydroxyurea
IUPAC Traditional name
1-[1-(1-benzothiophen-2-yl)(2H4)ethyl]-1-hydroxyurea
Synonyms
Abbott 64077-d4
Zyflo-d4
A-64077-d4
N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxyurea-d4
Leutrol-d4

DATABASE IDS

CAS Number 1189878-76-9

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 153-155°C
Solubility DMSO
Solubility Methanol
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
An inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. Used as an antiasthmatic.

REFERENCES

  • Carter, G.W., et al.: J. Pharmacol. Exp. Ther., 256, 929 (1991)
  • Weinblatt, M.E., et al.: J. Rheumatol., 19, 1537 (1991)
  • McGill, K and Busse, W.W.: Lancet, 348, 519 (1996)