Withaferin A

• Catalog No.: W499200
• CAS Number: 5119-48-2
• M. F.: C28H38O6
• M. W.: 470.59772
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1S,2R,6S,7R,9R,11S,12S,15R,16S)-6-hydroxy-15-[(1S)-1-[(2R)-5-(hydroxymethyl)-4-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]ethyl]-2,16-dimethyl-8-oxapentacyclo[9.7.0.0^2,^7.0^7,^9.0^1^2,^1^6]octadec-4-en-3-one
• IUPAC Traditional name: withaferin A
• Synonyms: Withaferine; Withaferine A; NSC 273757; (4β,5β,6β,22R)-5,6-Epoxy-4,22,27-trihydroxy-1-oxoergosta-2,24-dien-26-oic Acid δ-Lactone; (20S,22R)-5,6β-Epoxy-4β,22,27-trihydroxy-1-oxo-5β-ergosta-2,24-dien-26-oic Acid δ-Lactone; NSC 101088

DATABASE IDS

• CAS Number: 5119-48-2

PROPERTIES

• Apperance: White Solid
• Melting Point: 228-230°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Withaferin A is a promising anticancer constituent of Ayurvedic medicinal plant Withania somnifera. Withaferin A showed potent cytotoxicity against human head and neck squamous cell carcinoma (JMAR and MDA-1986).

REFERENCES

• Shohat, B., et al.: Cancer Chemother. Rep., 51, 271 (1967)
• Shohat, B., et al.: Int. J. Cancer., 8, 487 (1967)