WAY 267464 Dihydrochloride

• Catalog No.: W498600
• CAS Number: 847375-16-0
• M. F.: C32H35N7O4
• M. W.: 581.6648

SYNONYMS

• IUPAC name: 4-[(3,5-dihydroxyphenyl)methyl]-N-[(2-methyl-4-{4-methyl-2,4,5,9-tetraazatricyclo[8.4.0.0^3,^7]tetradeca-1(10),3(7),5,11,13-pentaene-9-carbonyl}phenyl)methyl]piperazine-1-carboxamide
• IUPAC Traditional name: 4-[(3,5-dihydroxyphenyl)methyl]-N-[(2-methyl-4-{4-methyl-2,4,5,9-tetraazatricyclo[8.4.0.0^3,^7]tetradeca-1(10),3(7),5,11,13-pentaene-9-carbonyl}phenyl)methyl]piperazine-1-carboxamide
• Synonyms: N-[[4-[(4,10-Dihydro-1-methylpyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]-2-methylphenyl]methyl]-4-[(3,5-dihydroxyphenyl)methyl]-1-piperazinecarboxamide Dihydrochloride

DATABASE IDS

• CAS Number: 847375-16-0

DETAILS

Description (English)

WAY 267464 is a potent, selective non-peptide oxytocin receptor (OTR) agonist (Ki = 58.4 nM at human OTR). WAY 267464 exhibits anxiolytic-like effects. May have therapeutic potential for the treatment of psychosis and schizophrenia.

REFERENCES

• Burbach, J., et al.: J. Biol. Chem., 258, 1487 (1983)
• Amico, J., et al.: Pharmacol. Biochem. Behav., 78, 333 (1983)
• Ashworth, D., et al.: Drugs Future, 31, 345 (1983)
• Ring, et al.: Neuropharmacology, 58, 6 (1983)