Voriconazole-d3 N-Oxide

• Catalog No.: V760012
• M. F.: C16H14F3N5O2
• M. W.: 365.3098696
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 4-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)(1,1,1-^2H₃)butan-2-yl]-5-fluoropyrimidin-1-ium-1-olate
• IUPAC Traditional name: 4-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)(1,1,1-^2H₃)butan-2-yl]-5-fluoropyrimidin-1-ium-1-olate
• Synonyms: UK 121265-d3; (αR,βS)-α-(2,4-Difluorophenyl)-5-fluoro-β-methyl-d3-α-(1H-1,2,4-triazol-1-ylmethyl)-1-oxide-4-pyrimidineethanol

PROPERTIES

• Solubility: Ethyl Acetate
• Apperance: Off-White Solid
• Melting Point: 67-69°C
• Solubility: Chloroform
• Solubility: Dichloromethane
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A labelled metabolite of Voriconazole (V760000).

REFERENCES

• Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997)
• Geist, M., et al.: Antimicrob. Agents. Chemother., 50, 3227 (1997)
• Yamazaki, H., et al.: Drug. Metab. Dispos., 34, 1803 (1997)
• Yamazaki, H., et al.: Xenobiotica, 36, 1201 (1997)