O2-Vinyl 1-(Pyrrolidin-1-yl)diazen-1-ium-1,2-diolate

• Catalog No.: V500000
• CAS Number: 179344-98-0
• M. F.: C6H11N3O2
• M. W.: 157.17044

SYNONYMS

• IUPAC name: (ethenyloxy)[(Z)-(pyrrolidin-1-yl)-oxo-$l^{5}-azanylidene]amine
• IUPAC Traditional name: (ethenyloxy)[(Z)-pyrrolidin-1-yl-oxo-$l^{5}-azanylidene]amine
• Synonyms: V-PYRRO/NO; 1-[(Ethenyloxy)-NNO-azoxy]-pyrrolidine; 1-(Ethenyloxy)-3-(2-pyrrolidinyl)-3-(5-pyrrolidinyl)-1-triazenamine 2-oxide

DATABASE IDS

• CAS Number: 179344-98-0

PROPERTIES

• Apperance: Pale Yellow Oil
• Solubility: Ethanol
• Storage Warning: Store in Freezer (> 1 year at -20°C)

DETAILS

Description (English)

V-PYRRO/NO is a metabolically activated nitric oxide (NO) donor drug that can be used to selectively target NO delivery to the liver. The compound is metabolized by the liver, and spontaneously decomposes with a half-life of 3 seconds, liberating NO. In

REFERENCES

• Saavedra, J., et al.: J. Med. Chem., 40, 1947 (1997)
• Liu, J., et al.: J. Pharmacol. Exp. Ther., 310, 18 (1997)
• Lluch, P., et al.: J. Hepatol., 41, 55 (1997)
• Liu, J., et al.: Toxicology, 208, 289 (1997)