Vinblastine-d3

• Catalog No.: V314003
• M. F.: C46H58N4O9
• M. W.: 810.97412
• Storage: Refrigerator

SYNONYMS

• IUPAC name: methyl (1R,9R,10S,11S,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-[(^2H₃)methoxycarbonyl]-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2,4,6,13-tetraene-10-carboxylate
• IUPAC Traditional name: methyl (1R,9R,10S,11S,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(1S,13S,15S,17S)-17-ethyl-17-hydroxy-13-[(^2H₃)methoxycarbonyl]-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2,4,6,13-tetraene-10-carboxylate
• Synonyms: Rozevin-d3; (+)-Vinblastine-d3 Sulfate; 29060-LE-d3; Velbe-d3; Exal-d3; Velban-d3; Vincaleukoblastine-d3 Sulfate; VLB-d3; Valban-d3; Vinblastin-d3

PROPERTIES

• Apperance: Beige Solid
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Dimethyl Sulfoxide
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

Labelled Vinblastine (V314000). Antitumor alkaloid isolated from periwinkle, Vinca rosea Linn., Apocynaceae; inhibits microtubule assembly. An antineoplastic.

REFERENCES

• Lu, C., et al.: Cancer Research, 39, 3575 (1979)
• Gobbi, P.G., et al.: J. Clin. Oncol., 14, 527 (1979)
• Muhtadi, F.J., et al.: Anal. Profiles Drug Subs. Excip., 21, 611 (1979)