Vinblastine Sulfate

• Catalog No.: V314000
• CAS Number: 143-67-9
• M. F.: C46H60N4O13S
• M. W.: 909.0526
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: sulfuric acid methyl (1R,9R,10S,11R,12R)-11-(acetyloxy)-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2,4,6,13-tetraene-10-carboxylate
• IUPAC Traditional name: sulfuric acid methyl (1R,9R,10S,11R,12R)-11-(acetyloxy)-12-ethyl-4-[(1S,13S,15S,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2,4,6,13-tetraene-10-carboxylate
• Synonyms: Exal; Vincaleukoblastine Sulfate; Velban; Vinblastin; (+)-Vinblastine Sulfate; Rozevin; VLB; Valban; 29060-LE; Velbe

DATABASE IDS

• CAS Number: 143-67-9

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: >200°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Antitumor alkaloid isolated from periwinkle, Vinca rosea Linn., Apocynaceae; inhibits microtubule assembly. An antineoplastic.

REFERENCES

• Lu, C., et al.: Cancer Research, 39, 3575 (1979)
• Gobbi, P.G., et al.: J. Clin. Oncol., 14, 527 (1979)
• Muhtadi, F.J., et al.: Anal. Profiles Drug Subs. Excip., 21, 611 (1979)