(R)-(+)-Verapamil-d6 Hydrochloride

• Catalog No.: V124992
• M. F.: C27H39ClN2O4
• M. W.: 491.06256

SYNONYMS

• IUPAC name: (2R)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-[(1,1,1,3,3,3-^2H₆)propan-2-yl]pentanenitrile hydrochloride
• IUPAC Traditional name: (2R)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-[(1,1,1,3,3,3-^2H₆)propan-2-yl]pentanenitrile hydrochloride
• Synonyms: NSC 632821-d6; Dexverapamil-d6 Hydrochloride; (R)-Verapamil-d6 Hydrochloride; LU 33925-d6; (αR)-α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)benzeneacetonitrile-d6 Hydrochloride

DETAILS

Description (English)

Labelled R-Verapamil (V124990). Both isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells.

REFERENCES

• Peroutka, S., et al.: J. Ann. Neurol, 23, 500 (1988)
• Eliason, J.F., et al.: Int. J. Cancer, 46, 113 (1988)