Varenicline Tartrate

• Catalog No.: V098490
• CAS Number: 375815-87-5
• M. F.: C17H19N3O6
• M. W.: 361.34926
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 2,3-dihydroxybutanedioic acid; 5,8,14-triazatetracyclo[10.3.1.0^2,^1^1.0^4,^9]hexadeca-2,4,6,8,10-pentaene
• IUPAC Traditional name: (.+-.)-tartaric acid; varenicline
• Synonyms: 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (2R,3R)-2,3- dihydroxybutanedioate; CP 526555-18; Champix

DATABASE IDS

• CAS Number: 375815-87-5

PROPERTIES

• Apperance: Tan Solid
• Melting Point: 206-208°C
• Solubility: DMSO
• Storage Condition: Refrigerator

DETAILS

Description (English)

Nicotinic α4β2 acetylcholine receptor partial agonist. Aid in smoking cessation.

REFERENCES

• Benowitz, N., et al.: Clin. Pharmacol. Ther., 44, 23 (1988)
• Cohen, C., et al.: J. Pharmacol. Exp. Ther., 306, 407 (1988)
• Tapper, A., et al.: Science, 306, 1029 (1988)
• Coe, J., et al.: J. Med. Chem., 48, 3474 (1988)
• Obach, R., et al.: Drug Metab. Disp